Functional and Cognitive Outcome in Prolonged Refractory Status Epilepticus

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Functional and cognitive outcome in prolonged refractory status epilepticus.

OBJECTIVE To determine the functional and cognitive outcomes of patients with prolonged refractory status epilepticus (PRSE) lasting 7 or more days despite the use of anesthetic agents for seizure suppression. DESIGN Retrospective analysis. SETTING St Mary's Hospital, Mayo Clinic, Rochester, Minnesota. PARTICIPANTS Fourteen patients with PRSE. INTERVENTION Hospital follow-up interview. ...

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Functional outcome of prolonged refractory status epilepticus

INTRODUCTION To characterize etiology, clinical course and outcomes of patients in prolonged refractory status epilepticus (PRSE) and looking for prognostic factors. METHODS Retrospective study conducted in patients hospitalized from January 1, 2001 to December 31, 2011 in 19 polyvalent intensive care units in French university and general hospitals. Patients were adults with a generalized co...

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Status epilepticus and refractory status epilepticus management.

Status epilepticus (SE) describes persistent or recurring seizures without a return to baseline mental status and is a common neurologic emergency. SE can occur in the context of epilepsy or may be symptomatic of a wide range of underlying etiologies. The clinician's aim is to rapidly institute care that simultaneously stabilizes the patient medically, identifies and manages any precipitant con...

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Cognitive Outcome of Status Epilepticus in Children

Epileptic encephalopathy encompasses conditions in which cognitive, motor, or sensory deficits result as a consequence of epileptic activity defining certain syndromes. It therefore represents a more severe subset of epilepsy, which can be generally characterized as frequent or severe seizures leading to cerebral dysfunction. This disturbance in cerebral functioning can in turn hinder, somewhat...

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Successful treatment of childhood prolonged refractory status epilepticus with lacosamide

Prolonged, refractory status epilepticus is a rare clinical syndrome that is associated with severe morbidity and mortality. Lacosamide is a newly approved medication for treatment of partial onset seizures in adults, which has a novel mechanism of action. Experimental data and recent reports suggest that lacosamide could be effective in status epilepticus. We report a child with prolonged, ref...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 2009

ISSN: 0003-9942

DOI: 10.1001/archneurol.2009.273